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HOME ›   For Researchers ›   APPLY FOR A GRANT ›

Target Advancement Program

DEADLINE

In
Review

The Michael J. Fox Foundation believes that a major hurdle in the development of promising treatments for Parkinson's disease (PD) is the need for well-validated targets linked to the disease process. By promoting critical target validation studies within academic and industry laboratories, MJFF investments can help de-risk subsequent drug development and ultimately accelerate the advancement of innovative therapies for Parkinson's patients. Part of our Edmond J. Safra Core Programs for PD Research, the Target Advancement program seeks to build robust evidence to rationalize biological pathways and targets for further translation into new Parkinson's treatments.

Target Advancement awards support research characterizing promising, novel PD-relevant targets or continuing target biology work on established PD targets. Preferred targets for this program already demonstrate links to PD in human patient populations. These awards are well-suited to projects in which hypothetical or experimental rationale for a target is compelling but limited, and study results can make the case for continuing (or discontinuing) a line of research. Full details are available in the RFA and application template below.

We will begin accepting applications for for our next funding cycle on March 11, 2019. 

 

Research Models

Projects designed to assess emerging PD targets in pre-clinical models, human cellular models and human tissue and fluid matrices are eligible for this initiative. Applicants are encouraged to leverage existing resources if possible. Studies utilizing biosamples available through MJFF-sponsored biospecimen collections or the Parkinson's Progressive Markers Initiative should not apply for funding through this initiative. Funding requests to support use of biosamples from these resources will be considered by the Foundation on a case-by-case basis. Please email resources@michaeljfox.org for more information.

Biological Mechanisms

Target Advancement Awards support target validation approaches and biology research on novel targets and possible convergence around established PD-relevant genetic and pathological pathways such as alpha-synuclein, GBA1, LRRK2 and Parkin/Pink1. Please note that MJFF has made significant investments in these high-priority targets and proposals to continue investigating in these areas will be considered against the existing MJFF portfolio.  

Deadlines

Pre-Proposals Due:

Full Proposal Invitations:

Full Proposals Due (by invite only):

Anticipated Award Announcement:

Anticipated Funding:












September 26, 2018, 5 p.m. ET

December 2018

January 22, 2019, 5 p.m. ET

April 2019

May 2019

 

FUNDING OPPORTUNITIES INFORMATIONAL WEBINAR

Watch on Demand

This webinar provides an overview of our Foundation's funding strategy, open funding opportunities, 
and the application and review processes
.

Watch Now

 

Funding Available

12- to 18-month grants

Up to $150,000

For more information, visit the Administrative Guidelines page.

Application Process

Download RFA and application template.

Log in or create account in the grant application portal.

Submit your completed application.

Download Template & Instructions

Please fill out the form to download the RFA and Application Template









 

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