With over 50 clinical trials funded or sponsored to date, The Michael J. Fox Foundation has firsthand experience of the challenges faced by trial investigators. The Foundation's Clinical Strategies Team partners with awardees to replicate trial best practices and keep clinical projects on schedule and on budget. Our staff and advisors work directly with awardees to optimize:
- protocol design
- budgeting and streamlined contracting
- trial operations
- recruitment and retention
To speak with a member of the Clinical Strategies Team, contact firstname.lastname@example.org.
Focus on Clinical Trial Recruitment
Because slow recruitment for Parkinson's disease clinical trials represents a significant roadblock to therapeutic breakthroughs, we focus particular efforts on supporting effective strategies to increase the flow of willing volunteers into Parkinson's disease trials.
MJFF has developed multiple tools for the research community at large to support recruitment for trials:
Fox Trial Finder
Fox Trial Finder is a web-based clinical trial matching tool to help speed clinical trial recruitment for Parkinson's research. Members of the research community are invited to register and post clinical trials. Registered trial team members can search a growing (de-identified) volunteer database to review thousands of potential matches and message anonymous volunteers.
Recruitment Best Practices Manual
Our Recruitment Best Practices Manual is a compilation of high-impact recruitment strategies developed and tested by trial teams around the globe in conjunction with The Michael J. Fox Foundation's Clinical Operations team. The manual is available at no cost to any clinical trial team.
Guide to Recruitment Planning
Based on MJFF's work with over a hundred trials to develop recruitment plans, this guide provides an off-the-shelf planning resource for study investigators and coordinators alike.
Worksheets and Handouts for Potential Volunteers:
In our work to help trial teams recruit clinical trial participants, we have created several handouts for teams to use for their trials. Patient handouts have been created for the following:
Other Trial Resources
Clinical Trials in Neurology: Design, Conduct, Analysis
MJFF Executive Scientific Advisory Board member Bernard Ravina, MD, MSCE, is the editor of Clinical Trials in Neurology: Design, Conduct, Analysis, published by Cambridge University Press. Jeffrey Cummings, Michael McDemott and R. Michael Poole are also editors. 100% of royalties from the sale of the book will benefit The Michael J. Fox Foundation for Parkinson's Research.
From the book description at Amazon, where the book is available for purchase:
"Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry."
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